The IOE has a particular relationship with Europe since most of its european members were members from the beginning. For more than forty years, the IOE European members have met each year in a different country in order to discuss topical issues for European employers. Current debates focus on globalization, CSR and outsourcing. The IOE works closely with its individual members in participating in a number of national events.

After the fall of communism in Europe, the IOE participated in the establishment and development of employers' organizations in transition countries. The IOE continues this work especially within the framework of the Stability Pact for the reconstruction of South Eastern Europe where it represents employers from this region. The IOE also works with its member federations in CIS countries to assist them in their development.

Regional integration is very important for Europe within the framework of the European Union. The IOE works closely with BUSINESSEUROPE on European social issues. The IOE also works directly with the European Commission at the ILO and in the Stability Pact for South Eastern Europe. nad is present on the Council of Europe is also an IOE partner due to its presence in the Council's Governmental Committee of the Social Charter and participates in activities in the Stability Pact for SEE.